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1

Application of advances in endocytosis and membrane trafficking to drug delivery

Ju, Yaping, Guo, Hao, Edman, Maria, Hamm-Alvarez, Sarah F.

Journal:

Advanced Drug Delivery Reviews

Year:

2020

File:

PDF, 3.56 MB

2020

2

Polystyrene nanoparticle trafficking across alveolar epithelium

Nazanin R. Yacobi, Lucas DeMaio, Jiansong Xie, Sarah F. Hamm-Alvarez, Zea Borok, Kwang-Jin Kim, Edward D. Crandall

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 614 KB

english, 2008

3

Cholinergic Stimulation of Lacrimal Acinar Cells Promotes Redistribution of Membrane-associated Kinesin and the Secretory Protein, β-hexosaminidase, and Increases Kinesin Motor Activity

SARAH F. HAMM-ALVAREZ, SILVIA DA COSTA, TAO YANG, XINHUA WEI, PETER J. GIEROW, AUSTIN K. MIRCHEFF

Journal:

Experimental Eye Research

Year:

1997

Language:

english

File:

PDF, 778 KB

english, 1997

4

Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjögren's syndrome-like exocrinopathy

Katja Schenke-Layland, Jiansong Xie, Mattias Magnusson, Ekaterini Angelis, Xiaodong Li, Kaijin Wu, Dieter P. Reinhardt, W. Robb MacLellan, Sarah F. Hamm-Alvarez

Journal:

Experimental Eye Research

Year:

2010

Language:

english

File:

PDF, 10.29 MB

english, 2010

5

Targeting receptor-mediated endocytotic pathways with nanoparticles: Rationale and advances

Xu, Shi, Olenyuk, Bogdan Z., Okamoto, Curtis T., Hamm-Alvarez, Sarah F.

Journal:

Advanced Drug Delivery Reviews

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

6

Myoepithelial cell-driven acini contraction in response to oxytocin receptor stimulation is impaired in lacrimal glands of Sjögren’s syndrome animal models

Hawley, Dillon, Tang, Xin, Zyrianova, Tatiana, Shah, Mihir, Janga, Srikanth, Letourneau, Alexandra, Schicht, Martin, Paulsen, Friedrich, Hamm-Alvarez, Sarah, Makarenkova, Helen P., Zoukhri, Driss

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.96 MB

english, 2018

7

Sjögren's autoimmunity: how perturbation of recognition in endomembrane traffic may provoke pathological recognition at the cell surface

Austin K. Mircheff, J. Peter Gierow, Tao Yang, Jian Zhang, Richard L. Wood, Ana Maria Azzarolo, Dwight W. Warren, Hongtao Zeng, Zhijun Guo, Harvey R. Kaslow, Sarah F. Hamm-Alvarez, Curtis T. Okamoto,

Journal:

Journal of Molecular Recognition

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

8

Changes in cytoskeletal organization in polyoma middle T antigen-transformed fibroblasts: Involvement of protein phosphatase 2A and src tyrosine kinases

Silvia R. da Costa, Yanru Wang, Patricia M. Vilalta, Axel H. Schönthal, Sarah F. Hamm-Alvarez

Journal:

Year:

2000

Language:

english

File:

PDF, 802 KB

english, 2000

9

Transferrin receptor recycling in rat hepatocytes is regulated by protein phosphatase 2A, possibly through effects on microtubule-dependent transport

M Runnegar, X Wei, N Berndt, S F Hamm-Alvarez

Journal:

Year:

1997

Language:

english

File:

PDF, 1.11 MB

english, 1997

10

Novel biphasic traffic of endocytosed EGF to recycling and degradative compartments in lacrimal gland acinar cells

Jiansong Xie, Limin Qian, Yanru Wang, Chadron M. Rose, Tao Yang, Tamako Nakamura, Sarah F. Hamm-Alvarez, Austin K. Mircheff

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

11

Biochemical Changes Contributing to Functional Quiescence in Lacrimal Gland Acinar Cells after Chronic Ex Vivo Exposure to a Muscarinic Agonist

L. Qian, Y. Wang, J. Xie, C. M. Rose, T. Yang, T. Nakamura, M. Sandberg, H. Zeng, J. E. Schechter, R. H. Chow, S. F. Hamm-Alvarez, A. K. Mircheff

Journal:

Scandinavian Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 6.11 MB

english, 2003

12

Quantitative second harmonic generation imaging of cartilage damage

Kelvin G. M. Brockbank, W. Robb MacLellan, Jiansong Xie, Sarah F. Hamm-Alvarez, Zhen Zhen Chen, Katja Schenke-Layland

Journal:

Cell and Tissue Banking

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

13

Use of nucleofection to efficiently transfect primary rabbit lacrimal gland acinar cells

Janette Contreras, Pang-Yu Hsueh, Hua Pei, Sarah F. Hamm-Alvarez

Journal:

Year:

2012

Language:

english

File:

PDF, 878 KB

english, 2012

14

Accumulation of Catalytically Active Proteases in Lacrimal Gland Acinar Cell Endosomes During Chronic Ex Vivo Muscarinic Receptor Stimulation

C. M. Rose, L. Qian, L. Hakim, Y. Wang, G. Y. Jerdeva, R. Marchelletta, T. Nakamura, S. F. Hamm-Alvarez, A. K. Mircheff

Journal:

Scandinavian Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005

15

Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1

Michael B. Bolger, Ian S. Haworth, Aaron K. Yeung, David Ann, Hermann von Grafenstein, Sarah Hamm-Alvarez, Curtis T. Okamoto, Kwang-Jin Kim, Sujit K. Basu, Sharon Wu, Vincent H. L. Lee

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 108 KB

english, 1998

16

Adenoviral capsid modulates secretory compartment organization and function in acinar epithelial cells from rabbit lacrimal gland

Wang, Y, Xie, J, Yarber, F A, Mazurek, C, Trousdale, M D, Medina-Kauwe, L K, Kasahara, N, Hamm-Alvarez, S F

Journal:

Year:

2004

Language:

english

File:

PDF, 443 KB

english, 2004

17

Typical and atypical trafficking pathways of Ad5 penton base recombinant protein: implications for gene transfer

Rentsendorj, A, Xie, J, MacVeigh, M, Agadjanian, H, Bass, S, Kim, D-H, Rossi, J, Hamm-Alvarez, S F, Medina-Kauwe, L K

Journal:

Year:

2006

Language:

english

File:

PDF, 794 KB

english, 2006

18

Nocodazole Treatment of CV-1 Cells Enhances Nuclear/Perinuclear Accumulation of Lipid-DNA Complexes and Increases Gene Expression

Jimmy Lindberg, Mary Ann M. Fernandez, J. Dezz Ropp, Sarah F. Hamm-Alvarez

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

19

Microtubule-based Motor Proteins: New Targets for Enhancing Drug Delivery?

Sarah F. Hamm-Alvarez

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 1.35 MB

1996

20

Paclitaxel and Nocodazole Differentially Alter Endocytosis in Cultured Cells

Sarah F Hamm-Alvarez, Manisha Sonee, Kathleen Loran-Goss, Wei-Chiang Shen

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 1.98 MB

1996

21

Stable Transfection of MDCK Cells with Epitope-Tagged Human PepT1

Chun Chu, Curtis T. Okamoto, Sarah F. Hamm-Alvarez, Vincent H. L. Lee

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

22

Endocytosis and sorting of macromolecules

Sarah F. Hamm-Alvarez, Curtis T. Okamoto

Journal:

Advanced Drug Delivery Reviews

Year:

2003

Language:

english

File:

PDF, 59 KB

english, 2003

23

Actin microfilaments et al.—the many components, effectors and regulators of epithelial cell endocytosis

Silvia R da Costa, Curtis T Okamoto, Sarah F Hamm-Alvarez

Journal:

Advanced Drug Delivery Reviews

Year:

2003

Language:

english

File:

PDF, 631 KB

english, 2003

24

Current status of gene delivery and gene therapy in lacrimal gland using viral vectors

Shivaram Selvam, Padmaja B. Thomas, Sarah F. Hamm-Alvarez, Joel E. Schechter, Douglas Stevenson, Austin K. Mircheff, Melvin D. Trousdale

Journal:

Advanced Drug Delivery Reviews

Year:

2006

Language:

english

File:

PDF, 451 KB

english, 2006

25

Mitochondrial medicine and mitochondrion-based therapeutics

Sarah Hamm-Alvarez, Enrique Cadenas

Journal:

Advanced Drug Delivery Reviews

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

26

Mitochondrial medicine and therapeutics, Part II

Sarah Hamm-Alvarez, Enrique Cadenas

Journal:

Advanced Drug Delivery Reviews

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

27

Modulation of secretory functions in epithelia by adenovirus capsid proteins

Sarah F. Hamm-Alvarez, Jiansong Xie, Yanru Wang, Lali K. Medina-Kauwe

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 751 KB

english, 2003

28

Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain

Guoyong Sun, Pang-Yu Hsueh, Siti M. Janib, Sarah Hamm-Alvarez, J. Andrew MacKay

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

29

Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways

Janette Contreras, Ahmed Y.O. Elnagar, Sarah F. Hamm-Alvarez, Julio A. Camarero

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

30

Polystyrene nanoparticle trafficking across MDCK-II

Farnoosh Fazlollahi, Susanne Angelow, Nazanin R. Yacobi, Ronald Marchelletta, Alan S.L. Yu, Sarah F. Hamm-Alvarez, Zea Borok, Kwang-Jin Kim, Edward D. Crandall

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 943 KB

english, 2011

31

Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1

Vincent H.L Lee, Chun Chu, Erik Denny Mahlin, Sujit K Basu, David K Ann, Michael B Bolger, Ian S Haworth, Aaron K Yeung, Sharon K Wu, Sarah Hamm-Alvarez, Curtis T Okamoto

Journal:

Journal of Controlled Release

Year:

1999

Language:

english

File:

PDF, 883 KB

english, 1999

32

Molecular motors and their role in membrane traffic

Sarah F Hamm-Alvarez

Journal:

Advanced Drug Delivery Reviews

Year:

1998

Language:

english

File:

PDF, 364 KB

english, 1998

33

Targeting endocytosis and motor proteins to enhance DNA persistence

Sarah F. Hamm-Alvarez

Journal:

Pharmaceutical Science & Technology Today

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

34

Molecular Identification of a Role for Tyrosine 167 in the Function of the Human Intestinal Proton- Coupled Dipeptide Transporter (hPepT1)

Aaron K. Yeung, Sujit K. Basu, Sharon K. Wu, Chun Chu, Curtis T. Okamoto, Sarah F. Hamm-Alvarez, Hermann von Grafenstein, Wei-Chiang Shen, Kwang-Jin Kim, Michael B. Bolger, Ian S. Haworth, David K. An

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 494 KB

english, 1998

35

Identification of a Novel Taxol-Sensitive Kinase Activity Associated with the Cytoskeleton

Yanru Wang, Roger Duncan, David K. Ann, Sarah F. Hamm-Alvarez

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000

36

Heterotrimeric GTP-binding Proteins in the Lacrimal Acinar Cell Endomembrane System

Limin Qian, Tao Yang, Haishan Chen, Jiansong Xie, Hongtao Zeng, Dwight W. Warren, Michaela MacVeigh, Michele A. Meneray, Sarah F. Hamm-Alvarez, Austin K. Mircheff

Journal:

Experimental Eye Research

Year:

2002

Language:

english

File:

PDF, 400 KB

english, 2002

37

Optimized Preservation of Extracellular Matrix in Cardiac Tissues: Implications for Long-Term Graft Durability

Katja Schenke-Layland, Jiansong Xie, Sepideh Heydarkhan-Hagvall, Sarah F. Hamm-Alvarez, Ulrich A. Stock, Kelvin G.M. Brockbank, W. Robb MacLellan

Journal:

The Annals of Thoracic Surgery

Year:

2007

Language:

english

File:

PDF, 16.82 MB

english, 2007

38

57. Comparison of heart valve cryopreservation and storage methods

Kelvin G.M. Brockbank, Katja Schenke-Layland, W. Robb MacLellan, Jiansong Xie, Sarah Hamm-Alvarez, Zhen Chen, Elizabeth Greene, Simona Baicu, Ying C. Song

Journal:

Year:

2007

Language:

english

File:

PDF, 61 KB

english, 2007

39

Role of the microtubule cytoskeleton in traffic of EGF through the lacrimal acinar cell endomembrane network

Jiansong Xie, Limin Qian, Yanru Wang, Sarah F. Hamm-Alvarez, Austin K. Mircheff

Journal:

Experimental Eye Research

Year:

2004

Language:

english

File:

PDF, 895 KB

english, 2004

40

Altered traffic to the lysosome in an ex vivo lacrimal acinar cell model for chronic muscarinic receptor stimulation

Limin Qian, Jiansong Xie, Chadron M. Rose, Eunbyul Sou, Hongtao Zeng, Sarah F. Hamm-Alvarez, Austin K. Mircheff

Journal:

Experimental Eye Research

Year:

2004

Language:

english

File:

PDF, 505 KB

english, 2004

41

Male NOD mouse external lacrimal glands exhibit profound changes in the exocytotic pathway early in postnatal development

Silvia R. da Costa, Kaijin Wu, Michelle Mac Veigh, Mike Pidgeon, Chuanqing Ding, Joel E. Schechter, Sarah F. Hamm-Alvarez

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 1.11 MB

english, 2006

42

Molecular mechanisms of lacrimal acinar secretory vesicle exocytosis

Kaijin Wu, Galina V. Jerdeva, Silvia R. da Costa, Eunbyul Sou, Joel E. Schechter, Sarah F. Hamm-Alvarez

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

43

Integrin adhesion in regulation of lacrimal gland acinar cell secretion

Sofia V. Andersson, Sarah F. Hamm-Alvarez, J. Peter Gierow

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 392 KB

english, 2006

44

Traffic of endogenous, transduced, and endocytosed prolactin in rabbit lacrimal acinar cells

Yanru Wang, Christopher T. Chiu, Tamako Nakamura, Ameae M. Walker, Barbara Petridou, Melvin D. Trousdale, Sarah F. Hamm-Alvarez, Austin K. Mircheff, Joel E. Schechter

Journal:

Experimental Eye Research

Year:

2007

Language:

english

File:

PDF, 2.59 MB

english, 2007

45

Transduced viral IL-10 is exocytosed from lacrimal acinar secretory vesicles in a myosin-dependent manner in response to carbachol

Jiansong Xie, Ronald R. Marchelletta, Padmaja B. Thomas, Damon T. Jacobs, Francie A. Yarber, Richard E. Cheney, Sarah F. Hamm-Alvarez, Melvin D. Trousdale

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 2.12 MB

english, 2009

46

Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland

Kaijin Wu, Corrine Joffre, Xiaodong Li, Michelle MacVeigh-Aloni, Melinda Hom, Juliana Hwang, Chuanqing Ding, Stephane Gregoire, Lionel Bretillon, Jiang F. Zhong, Sarah F. Hamm-Alvarez

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 3.49 MB

english, 2009

47

Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome

Katja Schenke-Layland, Jiansong Xie, Ekaterini Angelis, Barry Starcher, Kaijin Wu, Iris Riemann, W. Robb MacLellan, Sarah F. Hamm-Alvarez

Journal:

Year:

2008

Language:

english

File:

PDF, 4.87 MB

english, 2008

48

A Tunable and Reversible Platform for the Intracellular Formation of Genetically Engineered Protein Microdomains

Pastuszka, Martha K., Janib, Siti M., Weitzhandler, Isaac, Okamoto, Curtis T., Hamm-Alvarez, Sarah, MacKay, J. Andrew

Journal:

Biomacromolecules

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

49

Mucosal Immunity and Self-Tolerance in the Ocular Surface System

Austin K. Mircheff, Yanru Wang, Magdalena De Saint Jean, Chuanqing Ding, Melvin D. Trousdale, Sarah F. Hamm-Alvarez, Joel E. Schechter

Journal:

The Ocular Surface

Year:

2005

Language:

english

File:

PDF, 1.27 MB

english, 2005

50

The Novel Myosin Motor, Myosin VC, Facilitates Stimulated Exocytosis in Rabbit Lacrimal Acinar Cells

Ronald R. Marchelletta, Galina Jerdeva, Liminy Qian, Leticia Salas, Damon Jacobs, Richard E. Cheney, Sarah F. Hamm-Alvarez

Journal:

The Ocular Surface

Year:

2005

Language:

english

File:

PDF, 111 KB

english, 2005